From  Phoenix, Arizona
West Valley (Sky Harbor): Take  I-10 West. I-10 is a 4-lane divided highway and the speed goes from 55 to 75  MPH, depending on what part of the city you are in.
    Once outside of the  city you will need to exit State Route 85 (southbound) (Exit #112). This highway  will take you on the outskirts of Buckeye and to Gila Bend. This is mostly a  2-lane highway but there are a couple passing lanes and plenty of passing  opportunity. Traffic is usually heavy on the weekends and there is a lot of  truck traffic. Be especially careful on this highway before the holiday weekends  and people are passing like crazy and without any regard for other drivers. The  trip from I-10 to Gila Bend is apx. 30 miles and the speed limit is 65  MPH.
    As you come into Gila Bend the speed gradually  reduces to 35 MPH in city limits. In Gila Bend there are gas stations (Shell,  Chevron, etc.), motels (Space Age/Best Western, etc.), eating establishments  (McDonalds, Taco Bell, Dairy Queen, Burger King, A&W, etc.) and convenience  stores. There are also auto and tire repair shops and a grocery store.
    Go  through town and look for the McDonald's (on your right). Right before McDonalds  is where State Route 85 continues. There is a sign that says ”Mexico”.  Make a  right turn onto SR85.
    This leg of the highway is 65 MPH and is heavily  traveled by Border Patrol and Highway Patrol. The speed limit is 65MPH and it is  a 2-lane highway with plenty of places to pass. From Gila Bend to Ajo is apx. 40  miles.
    Once you approach Ajo, the speed gradually reduces  down to 25MPH in the heart of the city. In Ajo there are gas stations (Shell,  Chevron, etc.), restaurants (Pizza Hut, DQ, Ajo Lily, Marcellas, etc.), various  mechanics, tire shops, Radio Shack, Circle K, a few ATM machines and a grocery  store.
    If you have not purchased Mexican insurance you can get in at a  number of places in Ajo - some are open very late on the weekends. If you have  extra time you can tour the Copper Mine and Cabeza Prieta Refuge.
    Continue all the way through the town of Ajo and continue on SR-85 to  Why. The leg of the trip is 10 miles and is a 2-lane highway. The speed limit is  65MPH and reduces down to 45MPH once you approach Why. Once you  get to Why there are a couple convenience stores at the Why Not Travel and  Flores Chevron. You can also purchase Mexican Insurance at either one of these  places. Outside of Why (going toward Tucson) there is a little Indian Casino for  those of you feeling lucky (Golden Ha:san).
    Continue on SR-85 and you will enter the Organ Pipe National Monument. The  speed limit is 65 MPH though sometimes it is not posted. This area harbors some  of the only Organ Pipe Cactus in the nation - there is also a place to camp and  a ranger station where you get some info. on the area. This area is patrolled by  Park Rangers (who DO issue tickets) and the Sherriff. Please use caution driving  through this area as there are a lot of lookie-loos who sometimes like to travel  25MPH. Many times people will pull off the road to take a photo (and not pull  completely off) or just stop in the middle of the road. They have widened the  shoulders on this 2-lane highway but you still need to be very, very careful  especially October - May and on the busy weekends. The Border Patrol is usually  pretty heavy through this area. During the rainy season, between Ajo and Why,  the washes have a tendency to fill become flooded.
    The trip from Why to  the Lukeville border (also known as ”Gringo Pass” is apx. 30 miles. At Gringo  Pass there is a cafe, grocery store (Bashas Food City), gas station, U.S. Post  Office, duty-free store, motel, RV park and storage. You can also purchase  Mexican insurance here or have copies made or get something notarized. The town  on the other side of Lukeville is Sonoyta, Sonora, Mexico. The border closes at  midnight (Mexican time is same as Arizona time) and reopens at 6:00 AM. If you  are going to take duty-free items across with you, you are allowed 2 cartons of  cigarettes and 3 liters of alcohol per person. If you would like more  information about crossing the border, driving in Mexico or what items can be  brought into Mexico duty visit the Rocky Point Times Information Page at www.rptimes.com.
    Once you cross the border at Sonoyta/Lukeville you will  head straight ahead. The speed limit through town is 40 kmH. Watch out for  children, pedestrians and slow moving vehicles. You will come to a fork in the  road - stay to your left (Pemex station on the right). You will stop at the stop  sign and make a left (this is where Hwy. 2 from the Baja comes into Sonoyta).  Cross over the bridge (Rio Sonoita) and keep to your right.  You will see an overhead green sign that says Puerto Peñasco (Hwy 8). Continue  on to your right and you will see Vazquez Liquors on your left. There is a stop  light just past Vazquez (the stop light never works). Continue ahead and you  will come to a school zone. There is a stop sign hidden in here (where the topes  are - speed bumps). Continue straight all the way through town and you will be  in Highway 8 and then it is a straight shot into Rocky Point (apx. 64 miles). It  is a nice 2-lane wide highway with plenty of places to pass and pull off.This  highway is traveled by State Police and they do have radar and they do issue  tickets. Speed limit is 90 Km/h for the most part.

Directions  from Phoenix
East Valley:  Take I-10 East toward Tucson and exit Queen Creek Road. Take a right off of I-10  (heading toward Maricopa) and turn at Hwy. 247 going toward Gila Bend. This will take you all the way to Gila Bend - click here for directions the rest of the way. 

Directions  from Tucson
    There are two ways you can leave from  Tucson. The first will take you through the Indian Reservation and the second  will take you across Highway 8 to Gila Bend. The Hwy. 8 route is longer mileage  wise but some claim it is faster because of the 4-lane highway, speed limit and  less traffic congestion. Take I-10 to I-19 South and exit off on Old Ajo Highway  (or get there somehow). This will be State Route 86 (West) and you will take  this all the way to Why. This is a 2-lane highway all the way and the speed  limit is 65 MPH. It is a beautiful drive and well worth it if you are not in a  hurry. It is heavily traveled by Reservation Police (who issue tickets) and you  do see an occasional stray cow. For directions from Why to the Border click here.
    The second way you can come is to take I-10  (heading toward Phoenix) to I-8 (west - heading toward Sand Diego and Gila  Bend). Both of these highways are 4-lane and only near Tucson is the speed limit  55 MPH, the rest of the way it is 65 MPH. This will take you right into Gila  Bend. Click here for directions from Gila Bend to the  border.

Directions from Yuma, Arizona
    There are two routes you can  take: One on the Mexican side and the other on the American side. It is  recommended that, if you are traveling at night or have not driven in Mexico  before, stick to the U.S. route.
    U.S. route: Take I-8 East from Yuma to  State Route 85 and head toward Gila Bend. Click here for  directions from Gila Bend to the border.
    Mexican Route: Head down State  Route 95 to the town of San Luis. Once you have come across the U.S./Mexican  Border you will make a left on Highway 2. This Mexican Highway will take you all  the way into the town of Sonoyta, which is 66 miles from Puerto Peñasco. You  will go through San Luis and many small towns along the way. The highway is  pretty narrow in some spots and most of the highway does not have shoulders for  you to pull off onto in the event something happens to your vehicle.  Highway 2  is the main artery from the Baja, which means it is heavily traveled and passing  in some spots is not possible. It is constantly being repaved and repainted.  Outside of San Luis there will be a checkpoint. Most of the time you are waved  through but you could be asked some questions about where you are traveling to,  coming from, and what you are carrying. There could possibly be Federales posted  along the highway and their mainpurpose is to look for guns and drugs. From San  Luis to Sonoyta is about 2½ hours and from Sonoyta to Puerto Peñasco is about 1  hour.
    Once you enter into Sonoyta, continue straight  until you reach the statue (Pemex station off to your left) - keep to your  right. If you go left you will end up going back to the U.S. Cross over the  bridge (Rio Sonoita) and keep to your right. Click here  for directions to Rocky Point.

Directions  from Southern California
    Buy a map! There are quite a few ways you can take from Southern California.  Depending on where you are located, you will have to decide the best route for  yourself. The two main arteries for getting you here are I-8 and I-10. How you  get to either one of these is up to you. You can take I-40 through Barstow and  Needles, and take Highway 95 through Havasu, come through Parker and down  through Quartzsite onto I-10. Or you can come down to I-8 and go through San  Diego toward Yuma, or go out through the Salton Sea. It is really best if you  invest in a map or consult AAA or a trip planning service.